姓名：荆耀彬 出生年月：1995年9月
政治面貌：中国共产党党员
邮箱：Yaobin_Jing@163.com
教育经历
2013年9月–2017年6月 首都师范大学 生物技术专业 理学学士
研究经历及成果展示
博士在读期间，共发表学术论文8篇 (IF > 10)。主要工作内容为：利用CRISPR激活筛选系统
手段揭示SOX5调控人干细胞衰老的分子机制，并基于此开发骨关节炎 (OA) 的基因治疗策略。
? 科研成果：
1. Jing Y# , Jiang X# , Ji Q, Wu Z, Wang W, Liu Z, Guillen-Garcia P, Esteban CR, Reddy P, Horvath S, Li J, Geng
L, Hu Q, Wang S, Belmonte JCI, Ren J, Zhang W, Qu J, Liu GH. Genome-wide CRISPR activation screening
in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation. Cell Stem Cell, 2023.
(IF=23.9；共一第一位)
2. Li LZ# , Yang K# , Jing Y# , Fan Y, Jiang X, Wang S, Liu GH, Qu J, Ma S, Zhang W. CRISPR-based screening
identifies XPO7 as a positive regulator of senescence. Protein Cell, 2023. (IF=21.1；共一第三位)
3. Zhang W# , Wan H# , Feng G# , Qu # J, Wang J, Jing Y, Ren R, Liu Z, Zhang L, Chen Z, Wang S, Zhao Y, Wang
Z, Yuan Y, Zhou Q, Li W, Liu GH, Hu B. SIRT6 deficiency results in developmental retardation in cynomolgus
monkeys. Nature, 2018. (IF=64.8；参与)
4. Cai Y# , Xiong M# , Xin Z# , Liu C# , Jie R# , Yang X, Lei J, Li W, Liu F, Chu Q, Yin J, Ye Y, Liu D, Fan Y, Sun S,
Jing Y, Zhao Q, Zhao L, Che S, Zheng Y, Yan H, Ma S, Wang S, Belmonte JCI, Qu J, Zhang W, Liu GH.
Decoding aging-dependent regenerative decline across tissues at single-cell resolution. Cell Stem Cell, 2023.
(IF=23.9；参与)
5. Zhang Y# , Zheng Y# , Wang S # , Fan Y, Ye Y, Jing Y, Liu Z, Yang S, Xiong M, Yang K, Hu J, Che S, Chu Q,
Song M, Liu GH, Zhang W, Ma S, Qu J. Single-nucleus transcriptomics reveals a gatekeeper role for FOXP1
in primate cardiac aging. Protein Cell, 2023. (IF=21.1；参与)
6. Ye Y, Yang K, Liu H, Yu Y, Song M, Huang D, Lei J, Zhang Y, Liu Z, Chu Q, Fan Y, Zhang S, Jing Y, Esteban
CR, Wang S, Belmonte JCI, Qu J, Zhang W, Liu GH. SIRT2 counteracts primate cardiac aging via
deacetylation of STAT3 that silences CDKN2B. Nature Aging, 2023. (IF=16.6；参与)
7. Hu H# , Ji Q# , Song M# , Ren J, Liu Z, Wang Z, Liu X, Yan K, Hu J, Jing Y, Wang S, Zhang W, Liu G H, Qu J.
ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatin. Nucleic Acids Research, 2020.
(IF=14.9；参与)
8. Zou Z# , Long X# , Zhao Q# , Zheng Y# , Song M# , Ma S, Jing Y, Wang S, He Y, Esteban CR, Yu N, Huang J,
Chan P, Chen T, Izpisua Belmonte JC, Zhang W, Qu J, Liu GH. A single-cell transcriptomic atlas of human
skin aging. Developmental Cell, 2021. (IF=11.8；参与)
? 申请国家专利2项
荣誉奖励
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